CEU MedTech Alumnus Among Researchers on the Potential of Anti-SARS-Cov-2 IgM in Improving Clinical Sensitivity

Centro Escolar University School of Medical Technology alumnus, Mr. Anselmo Fabros is one of the researchers behind the study titled “Anti-SARS-CoV-2 IgM improves clinical sensitivity early in disease discourse”.

As per the published study, specimens from 175 PCR-positive patients and 107 control specimens were analyzed using Abbott IgM and IgG, DiaSorin IgG, and Roche Total (IgA, IgG, IgM) assays. Sensitivity, specificity, cross-reactivity, concordance between assays, trends over time, positive predictive value (PPV), and negative predictive value (NPV) were determined.

“The host immune system reacts to the infection by SARS-CoV-2 by producing specific antibodies. IgM and IgG are the key elements of the immune system that provide early response to infection (IgM) and long-lasting protective immunity (IgG). As IgM is a marker of acute infection, it may be a useful tool to combine it with PCR (Swab Test) to improve sensitivity and specificity early in the disease course”, said Mr. Fabros.

Mr. Fabros, a graduate of Bachelor of Science in Medical Technology in 1997 is presently a Charge-Medical Laboratory Technologist at Biochemistry and Immunology, Toronto General Hospital in Toronto, Ontario, Canada.

The full text of the study can be accessed on the National Library of Medicine website through this link https://pubmed.ncbi.nlm.nih.gov/33476578/.

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